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Certain substituted tetracycline compounds of the methods of the invention improve upon use of, eg, doxycycline as preferred agents with which to modulate the inducible regulatory system featured in the methods of the invention.
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GWHS opened in September 1927 with 983 students and 35 licensed staff members; 56 seniors graduated in the first commencement.

Charles Everett (’29) from Ohio and William Oliver (’32) from Texas along with Curly Julian, Mrs. Barbara Jean Sullivan Hine, Bob Jones (’29), and Thelma Flack (’29) Henderson, created the 50-year-club in the summer of 1982. Bob Jones suggested a scholarship fund to be the glue used to hold the social group together.  Mr. Julian encouraged the attitude of continuity and growing the club each year with a new annual “class” welcomed at a May dinner presentation.

The first official meeting took place in the faculty lunch room at Washington High in September of 1982 with the following twelve Founders: Cloyd Julian with class of 1929’s Thelma Flack Henderson and Bob Jones plus 1930’s former mayor Phil Bayt, Pauline Klingensmith, Selby Crowder, and Delores Harden then class of 1931’s Edith Herreman Lewis and Irene Claus Peters then finally the class of 1932’s Kenneth Baldwin, Paul Partlow, Kathryn Murphy Brothers, and someone who failed penmenship.